Content reviewed by the PillRelax Healthcare Team | Last reviewed: September 2026
Zopiclone is one of the most commonly prescribed sleeping tablets in the United Kingdom. If your GP has recommended it or you are considering it for insomnia, this guide explains exactly what Zopiclone is, how it works, who it is suitable for, and what risks you should be aware of.
What Is Zopiclone?
Zopiclone is a non-benzodiazepine hypnotic medicine used for the short-term treatment of insomnia. It belongs to the cyclopyrrolone class and is available in the UK under its generic name and several brand names including Zimovane. It is a prescription-only medicine (POM) in the United Kingdom.
How Does Zopiclone Work?
Zopiclone works by enhancing the activity of gamma-aminobutyric acid (GABA) receptors in the brain. GABA is the primary inhibitory neurotransmitter of the central nervous system. By potentiating GABA activity, Zopiclone reduces the time it takes to fall asleep, decreases nighttime awakenings, and increases total sleep duration.
What Conditions Is Zopiclone Used For?
- Difficulty falling asleep (sleep onset insomnia)
- Frequent nighttime awakenings (sleep maintenance insomnia)
- Early morning waking
- Severe or disabling insomnia causing significant distress
Standard UK Dosage
The standard adult dose is Zopiclone 7.5mg taken shortly before bedtime. For adults over 65 or those with liver or kidney problems, the recommended starting dose is 3.75mg. The maximum licensed duration is 2-4 weeks. Source: NHS Zopiclone information.
Common Side Effects
- Bitter or metallic taste in the mouth (most common)
- Dry mouth
- Daytime drowsiness
- Dizziness and headache
- Nausea
Who Should Not Take Zopiclone?
- Children and young people under 18
- People with severe liver problems
- People with myasthenia gravis
- People with untreated sleep apnoea
- People with a history of drug or alcohol dependence
- Pregnant or breastfeeding women
Dependence Risk
Zopiclone carries a genuine risk of physical and psychological dependence, particularly with use beyond 2-4 weeks. Withdrawal symptoms can occur if stopped abruptly after prolonged use. Always reduce the dose gradually under medical supervision.
How Can I Get Zopiclone in the UK?
Zopiclone is available from your GP or from a regulated UK online pharmacy following a prescription or online consultation. Learn how to buy Zopiclone online safely at PillRelax
Frequently Asked Questions
Can I drink alcohol while taking Zopiclone?
No. Combining Zopiclone with alcohol significantly increases sedation and respiratory depression. It is dangerous and must be avoided.
Will I feel drowsy the next day?
Some people experience next-day drowsiness, particularly at 7.5mg. If this occurs, do not drive or operate machinery.
